Sermorelinacetate is a synthetic growth hormone releasing hormone (GHRH) with 29 amino acid polypeptide. It is the amino terminal fragment of endogenous growth hormone releasing hormone (GHRH) and has significant growth regulation effect. Blacklock et al. proposed that neuropeptides/neurotransmitters, hormones and cytokines are the "common language" of mutual regulation among the three major systems: nervous system, endocrine system and immune system. In addition to its own very fine regulatory mechanism, the immune system is also regulated by the neuro-endocrine - immune network.S'ermorelin / S'ermorelin Acetate is a truncated analog of GRF 1-44 that is naturally produced by the brain to stimulate pituitary production. The increased volume produced by the pituitary gland causes an increase in the production of Insu-Like Growth Factor-1 by the liver and results in the benefits of treatment provided to the adult patient.S'ermorelin / S'ermorelin acetate is the acetate salt of an amidated synthetic 29-amino acid peptide that corresponds to the amino-terminal segment of the naturally occurring consisting of 44 amino acid residues. It stimulates the pituitary gland to naturally produce increased amounts.S'ermorelin / S'ermorelin acetate shares similar structure, is a bio-identical synthetic hormone that is extremely effective in increasing the amount of G H. S'ermorelin acetate is a recently synthesized (man-made) peptide analogue of a naturally occurring hormone that is produced in the hypothalamus and stimulates and controls the production within the pituitary gland.
| S'ermorelin Spefication | 2mg/vial |
| S'ermorelin Synonyms | S'ermorelin acetate hydrate, GRF 1-29 NH2 |
| S'ermorelin CAS No. | 114466-38-5 |
| S'ermorelin MF | C149H246N44O42S |
| S'ermorelin MW | 3357.91 |
| S'ermorelin Usage | Xanthine oxidase inhibitor |
Function:Chemorelin acetate can improve the cellular immune function of immunosuppressed mice, indicating that it has a certain immunomodulatory effect, which can restore the suppressed immune function to close to the normal level, especially the effect of high dose, but there is no significant difference between high dose and low dose, indicating no dose dependence. The mechanism may be through promoting the release of growth hormone (GH), a kind of anterior pituitary hormone, which has a wide impact on the immune system, almost all the immune cells can promote differentiation and enhance the function. The regulation of GH on the immune system may be achieved by regulating the growth of lymphoid tissue. Therefore, the enhancement effect of sermorelin acetate on immune system may also be effected through GH. Another possibility is that sermorelin acetate itself has an immune-enhancing effect, the specific mechanism of which needs to be further studied.In addition, thymus and spleen indexes were measured, indicating that the thymus and spleen of immunocompromised mice could be significantly increased by sheremoriin acetate. Normal mice liver can macrophage remove 90% of the carbon particles, spleen macrophages engulf clear about 10% of the carbon grains, carbon clearance test in mice results show that the CY to make the body to gobble up ability to remove carbon, the acetic acid Murray house forests antagonism this is abate, improve the phagocytosis of mononuclear phagocytes, suggest it can strengthen the nonspecific immune function of mice.
Product Usage:S'ermorelin / S'ermorelin acetate has a wide range of positive effects. Due to its nature as a GHRH, s'ermorelin only increases the body's ability to produce more hormone, it is not an injection of hormone itself. In both a performance enhancing and general well-being sense, s'ermorelin has a wide array of benefits that make it a powerful and valuable substance.
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