Vinpocetine is a semisynthetic derivative of the vinca alkaloid vincamine (sometimes described as "a synthetic ethyl ester of apovincamine"),an extract from the lesser periwinkle plant.
Vinpocetine is reported to have cerebral blood-flow enhancing and neuroprotective effects, and is used as a drug in Eastern Europe for the treatment of cerebrovascular disorders and age-related memory impairment.
Vinpocetine is widely marketed as a supplement for vasodilation and as a nootropic for the improvement of memory and cerebral metabolism. Vinpocetine has been identified as a potent anti-inflammatory agent that might have a potential role in the treatment of Parkinson's disease and Alzheimer's disease.
| [Product Name] | Vinpocetine |
[Others Name]
| Ethyl (3alpha,16alpha)-eburnamenine-14-carboxylate |
| [Botanical Source] | Voacanga Seed |
| [Part Used] | Seed |
| [Active Ingredient] | Garcinia Combogia |
| [Specification] | 99% |
| [Apperence] | White or slightly yellow, crystalline powder |
| [Molecular Formula] | C22H26N2O2 |
| [CAS No.] | 42971-09-5 |
[Weight]
| 350.454 |
| Item | Specification | Result |
| Appearance | White or slightly yellow, crystalline powder | Conforms |
| Specific Rotation, C=1 [a]D20 | 127 ~ 134 | 130.1 |
| Melting Point | 149°~ 153° | 150° |
| Solubility | Practically insoluble in water, soluble in methylene chloride, slightly soluble in anhydrous ethanol. | Conforms |
| Assay (On dried basis) | 98.5 – 101.5% | 99.10%(HPLC) |
| Related Substances | Impurity A: 0.6% Max. | 0.16% |
| Impurity B: 0.5% Max. | 0.15% |
| Impurity C: 0.3% Max. | 0.07% |
| Impurity D: 0.5% Max. | 0.16% |
| Unspecified Impurity: 0.1% Max. | 0.03% |
| Total Impurity: 1.0% Max. | 0.55% |
| Heavy Metals | 10ppm Max. | Complies |
| Loss on Dried | 0.5% Max. | 0.17% |
| Sulphated Ash | 0.1% Max. | 0.02% |
| Storage | Cool & dry place. Keep away from heat. |
| Remark | The product of this batch by inspection conforms to the standard of EP7.0. |
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