Delta sleep-inducing peptide, abbreviated DSIP belongs to API Powder, is a neuropeptide that when infused into the mesodiencephalic ventricle of recipient rabbits induces spindle and delta EEG activity and reduced motor activities.
A modulation or 'programming' interaction of delta sleep-inducing Peptide Powder (DSIP) with endogenous opioid-peptidergic systems and exogenous intracerebrally . The induction of cerebral MAO-A activity, a pronounced influence on the circadian rhythms of locomotion and intracerebral neurotransmitter as well as plasma protein and cortisol concentrations has been reported. DSIP was also shown to counteract experimentally induced stress situations in animals.
An improvement of the psychomotor performance and the concentration capacity in humans beside sleep normalization and pronounced effects on withdrawal symptoms including pain states in alcoholics and opiate addicts was discovered. This encouraged a pilot study for a possible action of the peptide in humans suffering from chronic pronounced pain episodes. DSIP about Api Powder has stress-protective, antiseizure, and immunomodulating effects.
| | DSIP
|
| Sequence | Trp-Ala-Gly-Gly-Asp-Ala-Ser-Gly-Glu. |
| | 62568-57-4
|
| Molecular formula | C35H48N10O15
|
| Molecular weight
| 848.81 |
| | 1. Lyophilized powder vial: 2mg/vial, 10 vials/box 2. Bulk powder: 1g/bottle, 5g/bottle |
| | ISO9001
|
| Shipment | FedEX; DHL; UPS; TNT |
Function:
rabbits injected with delta-sleep-inducing peptide (DSIP), spindle activity increased and heart and respiratory rates moderately decreased. δ -sleep-inducing peptide (DSIP) can be used as a programming modulator of the superoperational level rather than as a transmitter of the operational level [1]. δ -sleep inducing peptide (DSIP; 40μg/ kg, IP) increased catalase and superoxide dismutase (SOD) activities and malondialdehyde (MDA) concentration in liver homogenate of acute stress rats, but the opposite effect was observed at 120
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